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  • Chem Sci Trans., 2015, 4(3),  pp 642-648  

    DOI:10.7598/cst2015.1021

    Research Article

    Synthesis, X-Ray Powder Diffraction Studies and Antimicrobial Activities of Novel Shiff Base Derivatives

  • V. M. BAROT1, S. A. GANDHI*2, U. H. PATEL3 and M. C. PATEL1
  • 1P. G. Center in Chemistry, Smt. S. M. Panchal Science College, Talod, Gujarat 383 215, India
    2Shree P. M. Patel College of Electronics and Communications, Anand, Gujarat 388 001, India
    3Department of Physics, Sardar Patel University, Vallabh Vidyanagar, Gujarat 388120, India
  • Abstract

    Schiff bases are an important class of organic compounds, which play and an important role in medicinal and pharmaceutical applications. The synthesized compounds, 1-(4-butoxy-2-hydroxyphenyl) ethylidene- benzohydrazide (I), 1-(4-butoxy-2-hydroxy phenyl) ethylidene-4-chloro benzohydrazide (II) and 1-(4-butoxy-2-hydroxy phenyl) ethylidene-4-methyl benzohydrazide (III) have been characterized by FTIR, 1H and 13C NMR. The structural characterizations of synthesized compounds (I, II and III) have been estimated by analyzing powder X-ray diffraction technique. It is observed that samples I and III have crystallized in triclinic system with Pi space group and sample II in monoclinic system with P21/n space group. The synthesized compounds have been screened for its antimicrobial and antifungal activities against different panel of organisms.

    Keywords

    Schiff base, Powder x-ray diffraction, Antimicrobial, Antifungal activities

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