Schiff bases are an important class of organic compounds, which play and an important role in medicinal and pharmaceutical applications. The synthesized compounds, 1-(4-butoxy-2-hydroxyphenyl) ethylidene- benzohydrazide (I), 1-(4-butoxy-2-hydroxy phenyl) ethylidene-4-chloro benzohydrazide (II) and 1-(4-butoxy-2-hydroxy phenyl) ethylidene-4-methyl benzohydrazide (III) have been characterized by FTIR, 1H and 13C NMR. The structural characterizations of synthesized compounds (I, II and III) have been estimated by analyzing powder X-ray diffraction technique. It is observed that samples I and III have crystallized in triclinic system with Pi space group and sample II in monoclinic system with P21/n space group. The synthesized compounds have been screened for its antimicrobial and antifungal activities against different panel of organisms.
Schiff base, Powder x-ray diffraction, Antimicrobial, Antifungal activities