The kinetics of the osmium(VIII) catalyzed oxidation of L-arginine by periodate has been studied spectrophotometrically in alkaline medium at 280 nm. The reaction is first order with respect to [catalyst]. The reaction showed second order dependence on [periodate], fractional order dependence on [alkali] and is independent of substrate. The oxidation product of the reaction was found to be α- keto acid. A plausible mechanism has been proposed. The energy of activation, Ea and entropy of activation, ΔS# were computed and are found to be 53.00 ±1.78 kJ mol-1 and -46.30 ± 5.34 JK-1mol-1 respectively.
Oxidation of L-arginine, Periodate, Osmium(VIII)