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  • Chem Sci Trans., 2015, 4(3),  pp 819-827  

    DOI:10.7598/cst2015.1063

    Research Article

    Syntheses, Characterization and Antimicrobial Activities of 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-(((3aR,5R)-3--5- disubstituted -3,3a-dihydro-2H-pyrazolo[3,4-d]thiazol-6(5H)-yl)amino)ethanone derivatives

  • SHRUTI SATBHAIYA* and O.P. CHOURASIA
  • Synthetic Organic Chemistry Laboratory, Department of Chemistry, Dr. H. S. Gour Vishwvidhyalaya, Sagar (M.P.), 470003, India
  • Abstract

    A series of novel benzotriazole thiazolo pyrazoline were synthesized. The structures of obtained compounds were identified by elemental as well as by spectroscopic analysis (1H NMR and 13C NMR). The possible antimicrobial and anti-tubercular actions of these compounds were also tested using S. aureus, E. coli, C. albicans and A. niger. Compounds containing electron withdrawing group have shown good activity against all bacteria but compounds containing electron donating group have shown promising activity against all fungus.

    Keywords

    Benzotriazole, Thiazole, Pyrazoline and Antimicrobial activity

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