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  • Chem Sci Trans., 2015, 4(4),  pp 1066-1070  

    DOI:10.7598/cst2015.1110

    Research Article

    Solvent Free Synthesis of Pyrimidine, Quinazolinone and Diazatricyclo Derivatives via Phase-Transfer Catalysis Method

  • AKBAR MOBINIKHALEDI1, NASER FOROUGHIFAR2, TAHERE MOSLEH1 and MAHSA JABBARPOUR1
  • 1Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran
    2Faculty of Chemistry, Tehran North Branch, Islamic Azad University, Tehran, Iran
  • Abstract

    A simple and practical green chemistry procedure for the synthesis of some pyrimidine, quinazolinone and diazatricyclo derivatives is described. These compounds were synthesized in good to high yields by a Biginelli-like reaction of urea/thiourea, aldehyde and ketone under solvent free conditions in the presence of triethyl benzyl ammonium chloride (TEBAC) as a catalyst

    Keywords

    Multicomponent, Biginelli, Solvent free, Catalyst, TEBAC

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