Abstract

Regioselective synthesis of 3(n(1,3dioxo1H-benzo[de]isoquinolin-2(3H)-yl)alkyl)-2-(4-substituted) phenylthiazolidine-4-carboxylic acid were performed by coupling of 2-aryl-thiazolidin-4-caboxylic acids respectively with N-(ω-bromoalkyl)-1,8-naphthalimideusing K₂CO₃ in DMF medium. The structure of all the new compounds was characterized by IR, ¹H NMR, ¹³C NMR and Mass spectral data.

Keywords

1,8-Naphthalimide, Terminal dibromoalkane, Coupling, N-(ω-bromoalkyl)-1,8-naphthalimide, Regioselective