Synthesis of 3(N(1,3dioxo 1<i>H</i> benzo[de]isoquinolin-2(3<i>H</i>)-yl)alkyl)-2-(4-substituted) phenylthiazolidine-4-carboxylic Acid

Chem Sci Trans., 2016, 5(1), pp 163-170

DOI:10.7598/cst2016.1172

Research Article

Synthesis of 3(N(1,3dioxo 1H benzo[de]isoquinolin-2(3H)-yl)alkyl)-2-(4-substituted) phenylthiazolidine-4-carboxylic Acid

Abstract

Regioselective synthesis of 3(n(1,3dioxo1H-benzo[de]isoquinolin-2(3H)-yl)alkyl)-2-(4-substituted) phenylthiazolidine-4-carboxylic acid were performed by coupling of 2-aryl-thiazolidin-4-caboxylic acids respectively with N-(ω-bromoalkyl)-1,8-naphthalimideusing K₂CO₃ in DMF medium. The structure of all the new compounds was characterized by IR, ¹H NMR, ¹³C NMR and Mass spectral data.