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  • Chem Sci Trans., 2016, 5(1),  pp 248-252  

    DOI:10.7598/cst2016.1180

    Research Article

    Determination of Ethanol Content in Medicated Syrups: A Comparison among Distillation, Titration and GC Methods

  • ANANADA KUDALE1, KHUDBUDIN MULANI1, RAGHUNATH TOCHE2, SHOBHA BORHADE3, BALASAHEB DAUNDKAR1 and BHAUSAHEB MORE1*
  • 1Directorate of Forensic Science Laboratories, Kalina, Santacruz (E), Mumbai-400098, M. S. India
    2Dept. of Chemistry, KTHM College, Nashik-422002, M. S., India
    3S. M. B. S. T. College, Sangamner-422605, Dist.-Ahmed Nagar, M. S., India
  • Abstract

    Determination of ethanol content in medicated syrups was studied. We analysed ten medicated syrups namely; Aswins Balant kadha, Aswins Balkadu, Aswins Balant kadha, Aswins Paripathadi Kadha, Sandu Draksharishta, Franco-Indian P Dexorange hematinic Syrup, Raptakos Brett & Co. Elixir Neogadine, Virbac Animal Health Brotone Vet, Heptoglobin, Chereyl Laboratories Minoxidil topical solution. The ethanol content in the medicated syrups was determined by simple distillation, titration and GS-HS method. After distillation, ethanol content was analysed by Anton Paar Alcohol analyser. Modified oxidation-diffusion method was used as titration method for determination of ethanol concentration. A new GC-HS method was developed for analysis of ethanol and all samples were analysed directly without dilution except Chereyl Laboratories Minoxidil topical solution. The result shows that, ethanol content from all three methods gives comparable values and those are within the labelled claim

    Keywords

    Forensic sciences, Ethanol content, Medicated syrups, Distillation, Titration, GC-HS

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