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  • Chem Sci Trans., 2016, 5(2),  pp 305-310  

    DOI:10.7598/cst2016.1190

    Research Article

    Conventional Synthesis, In Vitro Antimicrobial Activity and Calculation of Pharmacokinetic Properties of Thioether Derivatives of Quinoxaline

  • RICHA SAHU* and S. P. SHRIVASTAVA
  • Department of Chemistry, Synthetic Organic Chemistry Laboratory, Dr. Hari Singh Gour(Central) University, Sagar(M.P)- 470003, India
  • Abstract

    Different thioether derivatives of quinoxaline moiety have been synthesized by conventional method. All the prepared compounds were analyzed by IR and NMR spectral analysis followed by antimicrobial screening using disk diffusion (Kirby Baeur) method against pathogenic bacteria and fungi. Ciprofloxacin and fluconazole were used as a standard drug for the study. Among them compound 3i shows better activity in comparison with standard

    Keywords

    Quinoxaline, Antimicrobial activity, Pharmacokinetic property

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