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  • Chem Sci Trans., 2016, 5(2),  pp 325-334  

    DOI:10.7598/cst2016.1203

    Research Article

    Nano Copper Ferrite Catalysed Improved Procedure for One-Pot Synthesis of Poly Substituted Pyridine Derivatives

  • S. PAUL DOUGLAS*, B. SWATHI, M. RAVI KUMAR, Y. RAMESH, K. JAYA RAO, B. SATYANARAYANA and CH. PANDU NAIDU
  • Department of Engineering Chemistry, A.U. College of Engineering [A], Andhra University, Visakhapatnam-530 003, Andhra Pradesh, India
  • Abstract

    The studies on application of magnetically separable substituted nano ferrites towards the multicomponent one-pot synthesis of heterocyclic compounds were thoroughly investigated. The present study gives an efficient method for the one-pot three-component synthesis of poly substituted pyridine derivatives by the cyclo-condensation of aromatic aldehyde, malononitrile and substituted phenols in the presence of magnetically recoverable nano copper ferrite catalyst. This method involves improved advantages like low percentage of catalyst used, lesser reaction times, higher yields, magnetic recoverability and reuse of the catalyst, which makes it an environmentally benign process.

    Keywords

    Nano copper-ferrite, Magnetically separable catalyst, One-pot multi-component synthesis, Poly substituted pyridines

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