• image 01
    Volume 1, No.1, 2012
  • image 02
    Volume 1, No.2, 2012
  • image 01
    Volume 1, No.3, 2012
  • image 02
    Volume 2, No.1, 2013
  • image 02
    Volume 2, No.2, 2013
  • image 02
    Volume 2, No.S1, 2013
  • image 02
    Volume 2, No.3, 2013
  • image 02
    Volume 2, No.4, 2013
  • image 02
    Volume 3, No.1, 2014
  • image 02
    Volume 3, No.2, 2014
  • Volume 3, No3
    Volume 3, No.3, 2014
  • Volume 3, No4
    Volume 3, No.4, 2014
  • Volume 4, No1
    Volume 4, No.1, 2015
  • Volume 4, No2
    Volume 4, No.2, 2015
  • Volume 4, No3
    Volume 4, No.3, 2015
  • Volume 4, No4
    Volume 4, No.4, 2015
  • Volume 5, No1
    Volume 5, No.1, 2016
  • image 01
  • image 02
  • Login|Register
  • Chem Sci Trans., 2016, 5(3),  pp 700-710  

    DOI:10.7598/cst2016.1227

    Research Article

    Molecular Docking Study of Some Novel Nitro- imidazo[1,2-b]pyridazine based Heterocyclics on Methicillin Resistant Staphylococcus aureus

  • P. K. RAMAN, K. MURALI KRISHNA and P. VENKATA RAMANA*
  • Department of Chemistry, Sri Krishnadevaraya University, Ananthapuramu-515 003, A.P., India
  • Abstract

    In this work, we selected three dimensional structure of Peptidoglycon which plays an important role in staphylococcus pathway. The protein structures were collected from PDB data bank. From the 3D structures of the proteins, the targeted derivatives were designed. Docking studies was performed with designed ligands from the drug. The drug derivatives docked to the protein by hydrogen boding interactions and these interactions play an important role in the binding studies. Docking results showed the best compounds among the derivatives.

    Keywords

    Antibacterial activity, Docking studies, Peptidoglycon, Nitroimidazo[1,2-b]pyridazine.

    This article has been viwed 689 times

      

    Citations for this article 0

      

    No Citations