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  • Chem Sci Trans., 2017, 6(1),  pp 1-7  

    DOI:10.7598/cst2017.1277

    Research Article

    Microwave Promoted Sodium Acetate Catalyzed One Pot Synthesis of Highly Functionalized Pyridine Derivatives

  • M. S. PANDHARPATTE1, HASSAN.A.OSMAN,ABU-BKER.M.OSMAN and G. M. NAZERUDDIN*
  • *Department of Chemistry, Poona College of Arts, Science & Commerce, Pune, India
    Department of Chemistry, Nowrosjee Wadia College of Arts and Science, Pune, India
    Department of Chemistry Nyala University, Nyala, Sudan
    Department of Chemistry, Science and Arts College for girls (Suratabidha), Saudi Arabia
  • Abstract

    A simple and efficient microwave promoted one pot synthesis of highly functionalized pyridine derivatives using sodium acetate as a catalyst via three component condensations of aldehydes, malonitrile and thiols is described. It is an efficient and promising synthetic protocol to build the highly functionalized pyridine derivatives

    Keywords

    Multi-component reaction, Highly functionalized pyridines derivatives, Sodium acetate

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