Abstract

Simple, selective and accurate differential first derivative spectrophotometric method (ΔD₁) was developed for the determination of florfenicol in bulk and pharmaceutical formulation. The developed method was based on measuring the ΔD₁ of florfenicol in alkaline solutions against its aqueous solutions as blank. Beer's law was found to be linear over the concentration range 3-15 μg/mL with good correlation coefficient (0.999). The selectivity of the method was proved through freedom from interferences

Keywords

Differential, First derivative, Florfenicol, Alkaline solutions