Abstract

Electrochemical studies of bupropion by voltammetric techniques were carried out. The bupropion gave one well-defined reduction peak at -1.2 to -1.3V vs. Ag/AgCl electrode in Britton Robinson buffer BR of pH 9. Under optimized conditions, a linear response was obtained between 1.0x10^-6 M to 5.6x10^-6 M in aqueous media for square wave and differential pulse cathodic adsorptive stripping voltammetric techniques. The electrochemical process was diffusion controlled. The value of limit of detection (LOD) are 1.28x10^-7 mol L^-1 and 7.79x10^-7 mol L^-1 for SWCAdSV and DPCAdSV respectively.

Keywords

Bupropion, Anti-depressant, Cyclic voltammetry, Glassy carbon electrode, Square wave voltammetry