• image 01
    Volume 1, No.1, 2012
  • image 02
    Volume 1, No.2, 2012
  • image 01
    Volume 1, No.3, 2012
  • image 02
    Volume 2, No.1, 2013
  • image 02
    Volume 2, No.2, 2013
  • image 02
    Volume 2, No.S1, 2013
  • image 02
    Volume 2, No.3, 2013
  • image 02
    Volume 2, No.4, 2013
  • image 02
    Volume 3, No.1, 2014
  • image 02
    Volume 3, No.2, 2014
  • Volume 3, No3
    Volume 3, No.3, 2014
  • Volume 3, No4
    Volume 3, No.4, 2014
  • Volume 4, No1
    Volume 4, No.1, 2015
  • Volume 4, No2
    Volume 4, No.2, 2015
  • Volume 4, No3
    Volume 4, No.3, 2015
  • Volume 4, No4
    Volume 4, No.4, 2015
  • Volume 5, No1
    Volume 5, No.1, 2016
  • image 01
  • image 02
  • Login|Register
  • Chem Sci Trans., 2017, 6(4),  pp 662-668  

    DOI:10.7598/cst2017.1404

    Research Article

    Spectrophotometric Determination of Vitamin C Using 3-Hydroxy-2-aryl-4H-chromen-4-one as Analytical Reagent

  • ASHWANIKUMAR* and PANKAJ BHATIA
  • Department of Chemistry, Kurukshetra University, Kurukshetra-136119, Haryana, India
  • Abstract

    A simple and rapid spectrophotometric method for the determination of ascorbic acid is described. It involves the reduction of iron(III) to iron(II) with ascorbic acid and the formation of brown coloured complex by the reaction of iron(III) with 3-hydroxy-2-aryl-4H-chromen-4-one, followed by the extraction of the complex into chloroform and measuring the absorbance at 405 nm. The Beers law is obeyed up to 2.4 μgmL-1 of ascorbic acid having molar absorptivity and Sandells sensitivity of 5.897x105L mol-1cm-1 and 2.986x10-4 μg cm-2 respectively. The interference of various substances commonly added to pharmaceuticals was studied. The procedure has been applied to the assay of pharmaceutical preparations containing vitamin C

    Keywords

    Spectrophotometry, Absorption, HAC, Ascorbic acid, Extraction

    This article has been viwed 98 times

      

    Citations for this article 0

      

    No Citations