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  • Chem Sci Trans., 2019, 8(4),  pp 437-447  

    DOI:10.7598/cst2019.1488

    Research Article

    Characteristics, Properties and Analytical Methods of Cefquinome - A Review

  • SHAZA W. SHANTIER
  • Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, P.O.Box-1996, Sudan
  • Abstract

    Drugs have been used for the treatment of infectious diseases since the 17th century. However, chemotherapy as a science began in the first decade of the 20th century with understanding of the principles of selective toxicity, the specific chemical relationships between microbial pathogens and drugs, the development of drug resistance and the role of combined therapy. Analysis of such drugs, whether used for treatment of human or animal illness, is essential in understanding the bioavailability and therapeutic control which will ensure their activity and safety. Thus, this review aims to highlight the characteristics, specifically the pharmacokinetic parameters and the analytical methods reported in literature for cefquinome, a fourth generation cephalosporine used to treat infections caused by gram-positive and gram-negative microorganisms.

    Keywords

    Infection, Antibiotics, Activity, Cefquinome, Cephalosporines

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