• image 01
    Volume 1, No.1, 2012
  • image 02
    Volume 1, No.2, 2012
  • image 01
    Volume 1, No.3, 2012
  • image 02
    Volume 2, No.1, 2013
  • image 02
    Volume 2, No.2, 2013
  • image 02
    Volume 2, No.S1, 2013
  • image 02
    Volume 2, No.3, 2013
  • image 02
    Volume 2, No.4, 2013
  • image 02
    Volume 3, No.1, 2014
  • image 02
    Volume 3, No.2, 2014
  • Volume 3, No3
    Volume 3, No.3, 2014
  • Volume 3, No4
    Volume 3, No.4, 2014
  • Volume 4, No1
    Volume 4, No.1, 2015
  • Volume 4, No2
    Volume 4, No.2, 2015
  • Volume 4, No3
    Volume 4, No.3, 2015
  • Volume 4, No4
    Volume 4, No.4, 2015
  • Volume 5, No1
    Volume 5, No.1, 2016
  • image 01
  • image 02
  • Login|Register
  • Chem Sci Trans., 2018, 7(3),  pp 362-373  

    DOI:10.7598/cst2018.1489

    Research Article

    Electrochemical Behaviour and Differential Pulse Cathodic Adsorptive Stripping Voltammetric Determination of Carmustine

  • SACHIN DOI, PRIYANKA SINHA and D. K. SHARMA*
  • Electrochemical Sensor Research Laboratory, Department of Chemistry, University of Rajasthan, Jaipur (Rajasthan)-302004, India
  • Abstract

    Electrochemical reduction properties of carmustine, an anticancer medication, were studied at glassy carbon electrode using cyclic voltammetry. A well defined irreversible reduction peak was obtained at -1.001V potential vs. Ag/AgCl reference electrode in BR buffer of pH 6.3. Mass transport in the reduction process was found to be diffusion controlled and a reduction mechanism was proposed on the basis of kinetic parameters which were calculated using experimental data. Furthermore, determination of carmustine in bulk form and human urine as a biological sample was carried out by differential pulse cathodic adsorptive stripping voltammetry using optimised parameters. Peak current was linear in the concentration range of 6.5x10-6-1.065x10-3M. LOD and LOQ were observed to be 4.16x10-7M and 1.39x10-6M respectively

    Keywords

    Carmustine, Cyclic voltammetry, Differential pulse cathodic adsorptive stripping voltammetry, Diffusion-controlled, LOD and LOQ

    This article has been viwed 177 times

      

    Citations for this article 0

      

    No Citations