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  • Chem Sci Trans., 2019, 8(3),  pp 359-367  

    DOI:10.7598/cst2019.1585

    Research Article

    Review on the Synthesis of α-Aminophosphonate Derivatives

  • R .A. SHASTRI
  • Post Graduate Department of Chemistry, S.B.E.S. College of Science, Aurangabad- 431001 (Maharashtra), India
  • Abstract

    α-Aminophosphonates are bioesters of amino acids and have several pharmacological activities. The high therapeutic properties of these compounds have encouraged researchers to synthesize new α-aminophosponate derivatives by Kabachnik field reaction and by Pudovik reaction by using different catalyst, under microwave irradiation, sonication etc. This article aims to review the work reported by researchers under different conditions and their biological activities.

    Keywords

    α-Aminophosphonates, Sonication, Kabachnik, Field reaction, Pundovik reaction, Catalyst

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