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  • Chem Sci Trans., 2019, 8(2),  pp 261-267  

    DOI:10.7598/cst2019.1586

    Research Article

    An Efficient Synthesis of Novel N,N-Dibenzoyl- pyrimidin-2(1H)-Ones Using Microwave Irradiation via Three-Component Biginelli Reaction

  • V. DEEPTHI, S.TRILOKNADH, B.NAGARAJU and C. VENKATA RAO*
  • Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
  • Abstract

    Environmentally benign microwave induced method of organic synthesis has been taken up to carry out three component Biginelli reaction for the synthesis of N,N-dibenzoyl pyrimidin-2-one derivatives. The advantages of this protocol include enhanced yield, reduced reaction time, operational simplicity, avoidance of organic solvents and eco-friendly preparation that directs towards new trends in green synthesis.

    Keywords

    Microwave induced organic synthesis, Biginelli reaction, N,N-dibenzoyl pyrimidin-2-one derivatives, green synthesis

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