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  • Chem Sci Trans., 2019, 8(4),  pp 487-492  

    DOI:10.7598/cst2019.20190008

    Research Article

    Synthesis, Characterization and Antioxidant Activity of Novel 3-(2,5-dioxo-imidazolidin-1-yl)-1,1-diethylurea Derivatives

  • H. N. DEEPAKUMARI1*, M. S. RAGHU2 and C. B. PRADEEP KUMAR3
  • 1Department of Chemistry, Bharathi College, Bharathinagara, Mandya-571422, India
    2Department of Chemistry, New Horizon College of Engineering, Bangalore-560103, India
    3Department of Chemistry, Malnad College of Engineering, Hassan?573202, India
  • Abstract

    A novel class of hydantoin derivatives was synthesized and their antioxidant activity was evaluated. The newly synthesized compounds were characterized using 1H NMR, IR, Mass spectra and elemental analysis. The antioxidant activity of synthesized compounds (3a-d) were examined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide hydroxyl radical scavenging assay. It is revealed from the antioxidant screening results that the compounds 3a and 3d manifested profound antioxidant potential.

    Keywords

    Hydantoin, DPPH, Nitric oxide, Antioxidant, Hydroxyl radical

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