• image 01
    Volume 1, No.1, 2012
  • image 02
    Volume 1, No.2, 2012
  • image 01
    Volume 1, No.3, 2012
  • image 02
    Volume 2, No.1, 2013
  • image 02
    Volume 2, No.2, 2013
  • image 02
    Volume 2, No.S1, 2013
  • image 02
    Volume 2, No.3, 2013
  • image 02
    Volume 2, No.4, 2013
  • image 02
    Volume 3, No.1, 2014
  • image 02
    Volume 3, No.2, 2014
  • Volume 3, No3
    Volume 3, No.3, 2014
  • Volume 3, No4
    Volume 3, No.4, 2014
  • Volume 4, No1
    Volume 4, No.1, 2015
  • Volume 4, No2
    Volume 4, No.2, 2015
  • Volume 4, No3
    Volume 4, No.3, 2015
  • Volume 4, No4
    Volume 4, No.4, 2015
  • Volume 5, No1
    Volume 5, No.1, 2016
  • image 01
  • image 02
  • Login|Register
  • Chem Sci Trans., 2013, 2(S1),  pp S105-S110  

    DOI:10.7598/cst2013.22

    Research Article

    Antimicrobial and Anticancer Activity of Gold Nanoparticles Synthesized from Grapes Fruit Extract

  • S. LOKINA and V. NARAYANAN
  • Rajalakshmi Engineering College, Thandalam, Chennai, Tamilnadu, India
    Department of Inorganic Chemistry, University of Madras, Chennai, Tamilnadu, India
  • Abstract

    Bio-inspired gold nanoparticles are rapidly synthesized at room temperature using grapes fruit extract. A green and low cost synthesis is effective in the formation of stable crystalline gold nanoparticles in the solution. Polyphenols which is present in the grapes fruit extract function as reducing as well as stabilizing agent to produce shape controlled gold nanoparticles. Surface plasmon resonance confirmed the formation of gold nanoparticles in UV-Visible spectra at 500 nm. The Fourier transform infrared spectroscopy (FTIR) analysis was carried out to identify and study the functional groups responsible for the bio-reduction of gold ion. High resolution transmission electron microscopy (HRTEM) images showed the spherical crystalline gold nanoparticles. Thermogravimetric analysis (TGA) measures the weight loss of gold nanoparticles as a function of temperature under a controlled atmosphere. The synthesized gold nanoparticles showed excellent antimicrobial activity towards most of the tested fungal and bacterial culture. It showed good anticancer activity against HeLa cell lines.

    Keywords

    Gold nanoparticles, Grapes, Polyphenols, Antimicrobial activity, Cytotoxicity

    This article has been viwed 4035 times

      

    Citations for this article 25

      

    Download Citations