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  • Chem Sci Trans., 2013, 2(1),  pp 246-250  

    DOI:10.7598/cst2013.280

    Research Article

    Synthesis and Chemical Characterization of 9-Anilinoacridines

  • RAJESH KUMAR, MANDEEP SINGH, D.N.PRASAD, OM SILAKARI and SARITA SHARMA
  • Department of Pharmaceutical Chemistry, Shivalik College of Pharmacy, Nangal, Punjab-140126, India
    Molecular Modeling Lab (MML), Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab-147002, India
    Department of Pharmaceutical Chemistry, Global College of Pharmacy, Khanpur Khuhi, Anandpur Sahib-140117, India
  • Abstract

    Chlorination of N-phenyl anthranilic acid (1) with phosphorus oxychloride affords 9-chloroacridine (2). Further these compounds were treated with aromatic amines to obtain 9-substituted acridine derivatives (3-9). All the synthesized compounds have been established on the basis of IR and 1H NMR spectra data.

    Keywords

    Cyclization, N-Methyl-2-pyrollidone, Acridine

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