N-[(Diphenylamino)methyl]acetamide was synthesized using Mannich reaction and its complexes of cerium(IV), thorium(IV) and dioxouranium(VI) were prepared and characterized by elemental analysis and various spectral studies. The bidendate chelation of ligand, bonding through carbonyl oxygen and azomethine nitrogen is suggested. Based on spectral and magnetic studies, hexa coordinate geometry is assigned for all the complexes. The complexes were screened for their antibacterial, antifungal and anticancer activities. They show positive results.
Physicochemical, Tuberculosis, Monosubstituted, Antimetabolite, Lipophilic