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  • Chem Sci Trans., 2013, 2(2),  pp 589-597  

    DOI:10.7598/cst2013.424

    Research Article

    Studies on Synthesis of Some New Sydnone Containing Compounds and Their Biological Activities

  • PIYUSH P. SAVALIYA, VIKUNJANA K. AKBARI and KESHAV C. PATEL
  • Department of Chemistry, Veer Narmad South Gujarat University, Surat-395007, Gujarat, India
  • Abstract

    Some new sydnone derivatives 3-[4-(morpholin-4-yl)phenyl]-4-(secondary substituted amino-4-yl methyl)-sydnone 6(a-j), 3-[4-(morpholin-4-yl) phenyl]-4-(secondary substituted amino-4-yl sulfonyl) sydnone 8(a-j) were synthesized starting from 4-chloroaniline (1). The characterization of the newly synthesized compounds was established by IR, 1H NMR, 13C NMR and Elemental analysis. The final compounds were tested for their antimicrobial activity against several microbes.

    Keywords

    Sydnone, Mesoionic, Antimicrobial activity

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