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  • Chem Sci Trans., 2013, 2(S1),  pp S330-S336  

    DOI:10.7598/cst2013.426

    Research Article

    A Green Protocol for One-Pot Three-Component Synthesis of Amidoalkyl Naphthols Catalyzed by Succinic Acid

  • NOURALLAH HAZERI, MALEK TAHER MAGHSOODLOU, SAYYED MOSTAFA HABIBI-KHORASSANI, JASEM ABOONAJMI and MOHYEDDIN SAFARZAEI
  • Department of Chemistry, The University of Sistan and Baluchestan, P.O.Box 98135-674, Zahedan, Iran
  • Abstract

    A green, genereal and efficient synthesis of amidoalkyl naphthols using succinic acid as a catalyst for the three-component condensation reaction of 2-naphthol, aldehydes and amides/urea under thermal solvent-free conditions is described. The advantages of this protocol are excellent yields, short reaction time, simple work-up, higher availability economical attraction, low cost catalyst, lack of toxicity and more environmentally friendly catalyst.

    Keywords

    Amidoalkyl naphthol, Three-component reaction, One-pot synthesis, Solvent-free

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