Intramolecular cyclization of 3-propargylmercapto-1,2,4-triazole derivatives (2) to their corresponding 6-methyl thiazolo[3,2-b][1,2,4]triazoles (3) was affected in the presence of nano catalyst, Fe(HSO4)3/TiO2 as solid acid in high yields.
Intramolecular cyclization, 3-Propargylmercapto-triazoles, Nano catalyst, Ferric hydrogen sulfate