Synthesis and Biological Activities of Some Novel Aminomethyl Derivatives of 5,5'-Butane-1,4-diyl-bis[4-allyl-2,4-dihydro-3<i>H</i>-1,2,4-triazole-3-thiones

Chem Sci Trans., 2013, 2(S1), pp S181-S191

DOI:10.7598/cst2013.480

Research Article

Synthesis and Biological Activities of Some Novel Aminomethyl Derivatives of 5,5'-Butane-1,4-diyl-bis[4-allyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones

Abstract

A series of aminomethyl containing 5,5'-butane-1,4-diyl-bis[4-allyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones were prepared under conventional cyclic condensation. The structures of newly synthesized compounds were established based on analytical and spectral studies. Further these compounds were evaluated for their antioxidant, antifungal and antibacterial activities. Most of the compounds showed good activity when compared with standard.