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  • Chem Sci Trans., 2013, 2(S1),  pp S181-S191  

    DOI:10.7598/cst2013.480

    Research Article

    Synthesis and Biological Activities of Some Novel Aminomethyl Derivatives of 5,5'-Butane-1,4-diyl-bis[4-allyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones

  • M. KOPARIR and C. OREK
  • Department of Chemistry, Faculty of Science, Firat University, 23119, Elazig, Turkey
  • Abstract

    A series of aminomethyl containing 5,5'-butane-1,4-diyl-bis[4-allyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones were prepared under conventional cyclic condensation. The structures of newly synthesized compounds were established based on analytical and spectral studies. Further these compounds were evaluated for their antioxidant, antifungal and antibacterial activities. Most of the compounds showed good activity when compared with standard.

    Keywords

    5,5'-Butane-1,4-diyl bis [4-allyl-2,4-dihydro-3H-1,2,4-triazole-3- thiones, Mannich bases, Biological activity

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