A simple and efficient method for the synthesis of a novel series of 2, 3, 5 trisubstituted indoles in high yields is discribed from an one-pot, three-component reaction of p-aniline, the phenylglyoxals and barbituric acid or dimedon in HOAc
Trisubstituted indoles synthesis, One-pot and three-component reaction, Aniline, phenylglyoxals, Barbituric acid, dimedon