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  • Chem Sci Trans., 2013, 2(4),  pp 1513-1517  

    DOI:10.7598/cst2013.600

    Research Article

    Synthesis of Bis(indolyl)methanes: A Natural Approach

  • MOHAMMED ZAMIR AHMED, C.B. KHILLARE and SHAIKH KABEER AHMED
  • P.G. Department of Chemistry, Sir Sayyad College of Arts, Commerce and Science, Aurangabad-431001(M.S.) India
    P.G. Department of Chemistry, Maulana Azad College, Aurangabad- (M.S.) India
  • Abstract

    An efficient and greener synthesis of bis(indoly)methanes was investigated via electrophilic substitution reaction of indole with carbonyl compounds in the presence of lemon juice as natural acid catalyst. The demonstrated environmentally benign protocol provided bis(indoly)methanes under mild reaction conditions, shorter reaction time and in excellent yield with simple work up procedure.

    Keywords

    Aldehydes, Ketones, Bis(indolyl)methanes, Natural catalyst

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