5-Ethyl-1,3,4-thiadiazole-2-amine have been synthesized by single step reaction. A series of heterocyclic azodyes were synthesized by coupling 8-hydroxyquinoline, 2,6-diaminopyridine, N,N-dimethyl aniline,
2-napthol and resorcinol with diazotized 5-ethyl-1,3,4-thiadiazol-2-amine in nitrosyl sulphuric acid. These dyes were characterized by UV, IR, 1H NMR, 13C NMR, elemental analysis and mass spectrometry for selected dyes. The synthesized compounds were also screened for biological activity.
5-Ethyl-1,3,4-thiadiazol-2-amine, 8-Hydroxy quinoline, 2,6-Diaminopyridine, N,N dimethyl aniline, 2-Napthol, Azo dyes, Antimicrobial activity