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  • Chem Sci Trans., 2014, 3(2),  pp 759-763  

    DOI:10.7598/cst2014.812

    Research Article

    A Study of Controlled Release of Aspirin by Mesoporous SBA-15

  • NEEL KAMAL KALITA and JATINDRA NATH GANGULI
  • Department of Chemistry, Gauhati University, Guwahati, Assam-781014, India
  • Abstract

    Mesoporous SBA-15 materials with high surface area were synthesized using hydrothermal method. These materials have large surface area, therefore good adsorber, besides the large pores offer sites for drug loading. The synthesized mesoporous materials were loaded with aspirin. Then controlled release of aspirin by the materials was studied in phosphate buffer system using UV- Visible spectrophotometer to monitor the concentration. The prepared samples were characterized by XRD, Nitrogen adsorption-desorption studies, TEM, IR and TGA. The benign nature of the SBA-15 materials makes it an ideal carrier for aspirin and facilitates the controlled release of the drug.

    Keywords

    Drug delivery, Mesoporous, SBA-15, Aspirin

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