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  • Chem Sci Trans., 2015, 4(1),  pp 258-262  

    DOI:10.7598/cst2015.978

    Research Article

    An Efficient One Pot Green Synthesis of 5-(Substituted Phenyl)-4H-1,2,4, triazol- 3- ols Under Ultrasonic Irradiation

  • SURENDER KUMAR
  • Department of Chemistry, Technological Institute of Textile & Sciences, Bhiwani, 127021, India
  • Abstract

    Here we describe the one pot efficient and eco-friendly synthesis of 5-(substituted phenyl)-4H-1,2,4 triazol-3-ols from benzaldehyde and semicarbazide hydrochloride using ultrasound irradiation avoiding toxic reagents. The combined use of 20 kHz US probe and 40 kHz US bath reduced the reaction time and improved the yield.

    Keywords

    1,2,4 Triazol-3-ols,Semicarbazide hydrochloride, Dual frequency ultrasonic irradiation

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