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Synthesis, Characterisation and DNA Binding Studies of Metal Complexes of Norfloxacin

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1TitleTitle of DocumentSynthesis, Characterisation and DNA Binding Studies of Metal Complexes of Norfloxacin
2CreatorAuthor's name, affiliation, country S. PUSHPALATHA
Department of Chemistry, Noorul Islam University, Kumaracoil, KK Dist, Tamilnadu, 629180, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Metal complexes, DNA binding studies, Viscosity method, Ligand
4DescriptionAbstract Metal complexes of tioconazole such as [Cu(nor)2(H2O) 2], [Zn(nor) 2 (H2O) 2], [Ni(nor) 2 (H2O) 2].4H2O and [Fe(nor) 2 (H2O)Cl].5H2O have been synthesized and characterised by elemental analysis, IR, UV-Visibe, ESR, NMR, XRD spectrscopic techniques. Thermal analysis was studied by TGA, DSC method. Morphological studies were carried out by scanning electron microscopic method. DNA binding studies were carried out by viscosity method. From the spectral studies an octahedral geometry was proposed for the copper complex. Prepared complexes showed enhanced DNA binding tendency than the parent drug that might be of interest for future research.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (1), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
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Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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