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Synthesis, Metal Ions Coordination, Antimicrobial Activity of Some L-Tartaric Acid Derivatives

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1TitleTitle of DocumentSynthesis, Metal Ions Coordination, Antimicrobial Activity of Some L-Tartaric Acid Derivatives
2CreatorAuthor's name, affiliation, country ZOULIKHA KHIATI, ABDELHAK CHERCHAR and ADIL A OTHMAN?
Laboratory of Bioactive Organic Chemistry-LCOB-, Department of Chemistry, Faculty of Science, University of Science and Technology-Mohamed Boudiaf-Oran,
USTO-MB.B.P.1505 ElMnaouer, 31000, Oran, Algeria
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 1,3,4-Oxadiazole-thione, 1,2,4-Triazole-thiol, L-Tartaric acid, Antimicrobial activity, Complex formation
4DescriptionAbstract The bis- 1,3,4-oxadiazole-thione and bis-4-amino-1,2,4-triazole-thiol derivatives from l-tartaric acid were synthesized. The synthetic intermediates, ester, hydrazide and oxadiazole derivatives have shown a significant tendency to form complexes with Fe(III),Ni(II) and Cu(II) ions. The formation of complexes with metals was detected by UV-Vis and IR spectroscopy. A novel complex nucleoside from bis-4-amino-1,2,4-triazole-thiol derivative with l-arabinose was also synthesized. The antimicrobial activity for final and synthetic intermediates in vitro against the microorganisms: Escherichia coli, Pseudomonas aeruginosa, Yersinia pseudotuberculosis, Enterococcus faecalis, Staphylococcus aureus and Candida albicans were examined and some products showed noticeable activity against the tested microorganisms.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2012.115
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  1 , Number  (1), (2012)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
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