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Synthesis of Some Novel 3, 5-Diaryl-N-chalcone-2-pyrazoline Derivatives and Evaluation of their Antimicrobial Activity |
DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Synthesis of Some Novel 3, 5-Diaryl-N-chalcone-2-pyrazoline Derivatives and Evaluation of their Antimicrobial Activity |
2 | Creator | Author's name, affiliation, country | SATISH BABULAL JADHAV* and SHANTILAL D. RATHOD P. G. Department of Chemistry, Milind College of Science,
Aurangabad-431002, Maharashtra, India
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3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | 2-Pyrazoline-1-carboxaldehyde, N-Chalcone, Formic acid, Hydrazine hydrate, Antibacterial, Antifungal activity |
4 | Description | Abstract | In the present investigation, a series of some novel 3,5-diaryl-N-chalcone-2-pyrazoline derivatives (6a-g) have been synthesized by the treatment of 4,5-dihydro-3-(2-hydroxyphenyl)-5-(6-methoxynaphthalen-5-yl)pyrazole-1-carbaldehyde (4a-g) with 2-hydroxy-4-chloro acetophenones (5) in presence of sodium hydroxide. The structure of newly synthesized compounds was confirmed by the IR, 1H NMR and Mass spectral analysis. All these newly synthesized compounds were evaluated for their in vitro antimicrobial activity. Most of the compound showed potent activity. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 5 , Number (1), (2016) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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