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Synthesis of Some Novel 3, 5-Diaryl-N-chalcone-2-pyrazoline Derivatives and Evaluation of their Antimicrobial Activity

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1TitleTitle of DocumentSynthesis of Some Novel 3, 5-Diaryl-N-chalcone-2-pyrazoline Derivatives and Evaluation of their Antimicrobial Activity
2CreatorAuthor's name, affiliation, country SATISH BABULAL JADHAV* and SHANTILAL D. RATHOD
P. G. Department of Chemistry, Milind College of Science, Aurangabad-431002, Maharashtra, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 2-Pyrazoline-1-carboxaldehyde, N-Chalcone, Formic acid, Hydrazine hydrate, Antibacterial, Antifungal activity
4DescriptionAbstract In the present investigation, a series of some novel 3,5-diaryl-N-chalcone-2-pyrazoline derivatives (6a-g) have been synthesized by the treatment of 4,5-dihydro-3-(2-hydroxyphenyl)-5-(6-methoxynaphthalen-5-yl)pyrazole-1-carbaldehyde (4a-g) with 2-hydroxy-4-chloro acetophenones (5) in presence of sodium hydroxide. The structure of newly synthesized compounds was confirmed by the IR, 1H NMR and Mass spectral analysis. All these newly synthesized compounds were evaluated for their in vitro antimicrobial activity. Most of the compound showed potent activity.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2016.1159
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (1), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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