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Synthesis, Characterization and Antimicrobial Activity of 5-Substituted indole-2,3-dione Based 4 -Thiazolidione Derivatives

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1TitleTitle of DocumentSynthesis, Characterization and Antimicrobial Activity of 5-Substituted indole-2,3-dione Based 4 -Thiazolidione Derivatives
2CreatorAuthor's name, affiliation, country A. ZAHIR HUSSAIN1, M. NAGOOR MEERAN2* and A. SANKAR3
1PG and Research Department of Chemistry, Jamal Mohamed College, Trichy, India
2PG and Research Department of Chemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Tiruchengode, India
3Department of Chemistry, Kandaswami Kandar?s College, P. Velur, Namakkal, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 5-Substituted indole -2,3-dione, Spiro-4-thiazolidiones, Antimicrobial
4DescriptionAbstract A series of 5-substituted indole- 2,3-dione based spiro-4-thiazolidiones were synthesized, characterization and evaluated for their antimicrobial activity. Condensation of 5-substituted indole-2,3-dione with substituted primary aryl amine was formed series of Schiff bases (1) which on reaction with thioglycolic acid and thiolactic acid in 1,4-dioxane afforded the formation of the corresponding 4-thiazolidinones (2, 3). All the synthesized compounds were characterized on the basis of their IR, 1H and 13C NMR and elemental analysis. The antimicrobial activity of all the compounds (D01-D04, E01-E04) showed significant activity against the selected micro organisms
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (1), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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