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Voltammetric Detection of Trimethoprim at CTAB Modified Carbon Paste Electrode

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1TitleTitle of DocumentVoltammetric Detection of Trimethoprim at CTAB Modified Carbon Paste Electrode
2CreatorAuthor's name, affiliation, country C. T. RAMYA KUMARI, G.P. MAMATHA* and H. M. SANTHOSH
Department of P.G. Studies and Research in Pharmaceutical Chemistry, Kadur Post Graduate center, Kuvempu University, Karnataka (S), India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Cyclic voltammetry, Trimethoprim, Cetyl trimethylammonium bromide, Carbon paste electrode
4DescriptionAbstract Cationic surfactant, cetyl trimethylammonium bromide (CTAB) modified carbon paste electrode was fabricated and it was applied to determine the electrochemical response of trimethoprim (TMP). The modified electrode shows excellent electrocatalytic activity towards the oxidation of TMP in phosphate buffer solution (PBS) of pH 3.0 by cyclic voltammetric and differential pulse voltammetric techniques. Cyclic voltammetric parameters such as pH, scan rate, concentration and effect of surfactant on TMP were studied. The analyte showed one well-resolved irreversible oxidation peak at around +1.17 V, which served as the analytical response. The scan rate study reveals that the electrode process was controlled by diffusion of the analyte. The limit of detection (LOD) and limit of quantification (LOQ) of trimethoprim were found to be 0.15 μ M and 0.455 μ M, respectively. CTAB modified carbon paste electrode showed excellent electrocatalytic effect towards the detection of trimetheoprim
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (3), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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