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Synthesis, Spectral Characterization and Biological Screening of Potentially Active 1, 3-Diones and its Transition Metal Complexes

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1TitleTitle of DocumentSynthesis, Spectral Characterization and Biological Screening of Potentially Active 1, 3-Diones and its Transition Metal Complexes
2CreatorAuthor's name, affiliation, country D. M. SURYAWANSHI, V. D. INGLE, N. A. BHISE, A. S. RAJBHOJ and S. T. GAIKWAD*
Department of Chemistry, Rayat Shikshan Sanstha?s Annasaheb Awate College, Manchar (M.S.), 410 503, India
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431 004, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords 1, 3-Diones, Metal complexes, Ultrasound irradiations, Magnetic measurements, Antibacterial screening
4DescriptionAbstract 1-(2-Hydroxyphenyl)-3-propane-1, 3-diones 4(LA-LB) and its metal complexes 5(a-e) have been newly synthesized from substituted 2-hydroxyacetophenones 1(A-B) and aromatic acids 2(A-B) under ultrasound irradiation method at low temperature. These compounds were characterized by FT-IR, UV-Vis., 1H-NMR, 13C-NMR, mass spectroscopy and magnetic measurement. The stoichiometry of the complexes was found 1:2 (metal:ligand). The physicochemical data suggested octahedral geometry for all the complexes. The ligands 4(LA-LB) and their metal complexes 5(a-e) were screened for in vitro antibacterial activity against S. aureus, B. subtilis, E. coli and P. aeruginosa compared with tetracycline and chloramphenicol as a standard drugs. The results are in good agreement with respect to activity of free ligand and its metal complexes. Reactions under ultrasonic irradiation had improved yield.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (4), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
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Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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