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Synthesis and Characterization of Potential Impurities in Levothyroxine

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1TitleTitle of DocumentSynthesis and Characterization of Potential Impurities in Levothyroxine
2CreatorAuthor's name, affiliation, country DEEPAK PANMANAD*, MANDAR JOSHI, RAHUL PATIL, PRIYANKA JOSHI and VIDYADHAR JADHAV
Prof. Dr. S. C. Bhattacharya Organic Synthesis Laboratory, VerGo Pharma Research Lab. Pvt. Ltd., Plot B5, Phase 1A, Verna Industrial Estate, Verna, Salcette, Goa-403722, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Levothyroxine, Impurity, Synthesis, Characterization, Decarboxylation
4DescriptionAbstract Five potential USP grade levothyroxine impurities i.e. N-methyl amide (2), T4-amine O-methyl (7), T4-acetamide (9), N-acyl-T4 (10) and N-formyl-T4 (11) have been synthesized. Each Levothyroxine impurity was characterized based on their spectral data (IR, 1H NMR and Mass). The synthesis and characterisation of the Levothyroxine impurities are discussed
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2016.1288
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  5 , Number  (4), (2016)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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