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Synthesis and Antimicrobial Activity of Some New 5-(Pyridin-4-yl)-3-thioacetamido-1,2,4-triazole

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1TitleTitle of DocumentSynthesis and Antimicrobial Activity of Some New 5-(Pyridin-4-yl)-3-thioacetamido-1,2,4-triazole
2CreatorAuthor's name, affiliation, country M.KARAARSLAN1, P.KOPARIR2*, A.CANSIZ3, C.OREK3 and O.SAP3
1Department of Chemistry, Forensic Medicine Institute, TR-4400, Malatya, Turkey
2Department of Chemistry, Aksaray, Universty, TR-68100, Aksaray, Turkey
3Department of Chemistry, Firat, University, TR-23119 Elazig, Turkey
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Triazole, Acetamido, Antimicrobial activity
4DescriptionAbstract A series of 5-(pyridin-4-yl)-3-thioacetamide-1,2,4-triazoles (4a-o), was synthesized, characterized and evaluated for screening antibacterial and antifungal activities on microorganisms, respectively on five bacteria and and Candida tropicalis. The structures of original compounds were confirmed by analytical and spectroscopic (FT-IR, 1H NMR and 13C NMR) methods and elemental analysis. Both the antibacterial and antifungal activities and MIC values of compounds were reported. Among the tested compounds, the most effective compound providing a MIC values of 64 g mL-1 are 4a,b aganist B. Subtilis and S. Typhimurium and 4o against E. Coli only.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2012.130
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  1 , Number  (1), (2012)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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