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Electrochemical Determination of Letrozole in Pharmaceutical Formulations by Advanced Voltammetric Techniques

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1TitleTitle of DocumentElectrochemical Determination of Letrozole in Pharmaceutical Formulations by Advanced Voltammetric Techniques
2CreatorAuthor's name, affiliation, country ANUBHA SHARMA, K. K. JHANKAL and D. K. SHARMA*
Electrochemical Research Laboratory, Department of Chemistry, University of Rajasthan, Jaipur (Rajasthan)- 302004, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Letrozole, Anti-Cancer, Cyclic voltammetry, Glassy carbon electrode, Square wave voltammetry
4DescriptionAbstract Electrochemical studies of letrozole by voltammetric techniques were carried out. The letrozole gave one well-defined reduction peak at -0.4 V to -0.5 V vs. Ag/AgCl electrode in Britton Robinson buffer BR of pH 7.0. Under optimized conditions, a linear response was obtained between 3.5x10-6 M and 1.0x10-4 M in aqueous media for square wave and differential pulse cathodic adsorptive stripping voltammetric techniques. The electrochemical process was diffusion controlled. The value of limit of detection (LOD) were 3.77x10−7 mol L−1 and 2.52x10-7 mol L−1 for SWCAdSV and DPCAdSV respectively.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2017.1320
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  6 , Number  (1), (2017)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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