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Total Structural Elucidation of Erlotinib and Gefitinib by Mainly 2D-Rotating Frame Overhauser Effect Spectroscopy (2D ROESY NMR) |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Total Structural Elucidation of Erlotinib and Gefitinib by Mainly 2D-Rotating Frame Overhauser Effect Spectroscopy (2D ROESY NMR) |
| 2 | Creator | Author's name, affiliation, country | CİGDEM KARAASLAN and HAKAN GOKER*
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Turkey
Central Instrumental Analysis Laboratory, Faculty of Pharmacy,
Ankara University 06100 Tandogan, Ankara-Turkey
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| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Erlotinib, Erlotinib HCl, Gefitinib, DEPT, COSY, ROESY, HSQC, HMBC. ROESY |
| 4 | Description | Abstract | Erlotinib HCl (TarcevaŽ) and Gefitinib (IressaŽ) are well known anticancer drugs, which are used in the treatment of several chemoresistant cancer. Their total structural assignments of Erlotinib, Erlotinib HCl and Gefitinib have been achieved by using 2D-NMR experiments, including DEPT, COSY, ROESY, HSQC and HMBC. ROESY experiment gives the best important data for their structural elucidation |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 6 , Number (2), (2017) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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