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Synthesis and Characterization of 1,3,4-Oxadiazoles Derivatives from 1,2,3,4-Tetrahydroisoquinoline and their Bioevalution (Antibacterial & Antifungal) |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis and Characterization of 1,3,4-Oxadiazoles Derivatives from 1,2,3,4-Tetrahydroisoquinoline and their Bioevalution (Antibacterial & Antifungal) |
| 2 | Creator | Author's name, affiliation, country | N. KRISHNA RAO1, M. SURENDRA BABU2*, M. V. BASAVESWARA RAO1,
R. KESHAVI3, N. SUNDARA RAO3, Y. L. N. MURTHY3 and SHAIK LAKSHMAN4
1Chemistry Department, Krishna University, Machilipatnam, India
2Department of Chemistry, GITAM University, Hyderabad, India
3Department of Organic Chemistry, Andhra University, Visakhapatnam, India
4Department of Chemistry, GITAM University, Visakhapatnam, India
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| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | 1,2,3,4-Tetrahydroisoquinoline, Ethyl-2-(1-phenyl-3,4-dihydro isoquinoline-2(1H)-yl) acetate, 2-(1-Phenyl-3,4-dihydroisoqunoline-2(1H)-yl)acetohydrazide, 1,3,4-Oxadiazole, Cyclization re |
| 4 | Description | Abstract | New derivatives of 1,3,4-oxadiazole, synthesized by the condensation of different substituted benzoic acids with 2-(1-phenyl-3,4-dihydroisoquinoline-2(1H)-yl) acetohydrazide using SOCl2 as well as POCl3 as cyclization reagents. Ethyl-2-(1-phenyl-1,2,3,4-tetrahydroisoquinoline)-ethaonate was synthesized from 1,2,3,4-Tetrahydroisoquinoline and it was converted to the 2-(1-phenyl-3,4-dihydroisoquinoline-2(1H)-yl)acetohydrazide. This compound is the key intermediate for the 1,3,4-oxadiazole compounds. All the synthesized molecules were characterized by advanced spectral data and also studied their biological activity. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 6 , Number (3), (2017) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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