DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Reaction of 4-Hydroxycoumarin with Salicylaldehyde: Products Formed Under Various Conditions and their Antiproliferative Activity |
2 | Creator | Author's name, affiliation, country | SHAZIA MUZAFFAR BANDAY and KHALIQUZ ZAMAN KHAN Department of Chemistry, University of Kashmir, Hazratbal, Srinagar,
Jammu & Kashmir, 190006, India
|
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | 4-Hydroxycoumarin, Salicylaldehyde, Antiproliferation |
4 | Description | Abstract | The reaction of 4-hydroxycoumarin with salicylaldehyde was carried out in ethanol and water-ethanol mixture (2:1 v/v) using conventional and microwave assisted methods. The reactions were explored leading to the formation of a single product in contrast to the two products formed usually, viz. 3-(o-hydroxybenzal)-2,4-diketochroman and 3-[6-oxo(1)benzopyran (4,3-b)-(1) benzopyran-7-yl]-4-hydroxy-2H-chromen-2-one. In addition to the exclusive formation of a single product, the time of reaction was reduced considerably. The products were evaluated for their antiproliferative activity and were found to exhibit good activity in comparison to the 4-hydroxycoumarin moiety. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 6 , Number (2), (2017) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |