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Spectrophotometric Determination of Vitamin C Using 3-Hydroxy-2-aryl-4H-chromen-4-one as Analytical Reagent

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1TitleTitle of DocumentSpectrophotometric Determination of Vitamin C Using 3-Hydroxy-2-aryl-4H-chromen-4-one as Analytical Reagent
2CreatorAuthor's name, affiliation, country ASHWANIKUMAR* and PANKAJ BHATIA
Department of Chemistry, Kurukshetra University, Kurukshetra-136119, Haryana, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Spectrophotometry, Absorption, HAC, Ascorbic acid, Extraction
4DescriptionAbstract A simple and rapid spectrophotometric method for the determination of ascorbic acid is described. It involves the reduction of iron(III) to iron(II) with ascorbic acid and the formation of brown coloured complex by the reaction of iron(III) with 3-hydroxy-2-aryl-4H-chromen-4-one, followed by the extraction of the complex into chloroform and measuring the absorbance at 405 nm. The Beers law is obeyed up to 2.4 μgmL-1 of ascorbic acid having molar absorptivity and Sandells sensitivity of 5.897x105L mol-1cm-1 and 2.986x10-4 μg cm-2 respectively. The interference of various substances commonly added to pharmaceuticals was studied. The procedure has been applied to the assay of pharmaceutical preparations containing vitamin C
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2017.1404
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  6 , Number  (4), (2017)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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