Indexing Metadata
Synthesis, Characterization and
In Vitro Antibacterial Effect of 4H-Benzo[g]chromene Derivatives using Nano-NiO
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DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
1 | Title | Title of Document | Synthesis, Characterization and
In Vitro Antibacterial Effect of 4H-Benzo[g]chromene Derivatives using Nano-NiO
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2 | Creator | Author's name, affiliation, country | T. CLARINA, G. R. PRIYA DHARSINI and V. RAMA* Department of Chemistry, Sarah Tucker College, Manonmaniam Sundarnar University, Abishekapatti, Tirunelveli -627 012, Tamilnadu, India |
3 | Subject | Dicipline(s) | Chemical Science |
3 | Subject | Keywords | Antibacterial, Knoevenagel condensation, Michael cyclization, Nano-NiO, Simple workup |
4 | Description | Abstract | The domino Knoevenagel cyclocondensation reactions via substituted aldehydes, activated methylene reagent and 2-hydroxy-1, 4-naphthoquinone gives benzo[g]chromenes in presence of nano-NiO using acetonitrile as a solvent at ambient temperature. This method gives the desired products from good to excellent yield. The salient features of this atom economical procedure are ease of manipulation, simpler workup, high yield processing, easy handling, inexpensiveness, reusability of catalyst and tolerance to a wide range of functional groups. The synthesized chromene derivatives are screened for antibacterial activity and antifungal activity using Kirby-Bauer method. The synthesized compounds 3a-3k exhibits significant inhibition to antibacterial and antifungal activity compared with the standard drug Ciprofloxacin and Flucanazole respectively. |
5 | Publishers | Organizing agency, location | WWW Publications, India |
6 | Contributor | Sponsor(s) | - |
7 | Date | Date (YYYY-MM-DD) | - |
8 | Type | Status & genre | Peer-reviewed Article |
8 | Type | Type | |
9 | Formate | File Formate | PDF |
10 | Identifier | Uniform Resource Identifier | Click Here |
10 | Identifier | Digital Object Identifier | |
11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 6 , Number (4), (2017) |
12 | Lanuguage | English=en | en |
13 | Relation | Supp.files | |
14 | Coverage | | - |
15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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