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One Pot Multicomponent Synthesis of Novel Thiazolopyrimidines

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1TitleTitle of DocumentOne Pot Multicomponent Synthesis of Novel Thiazolopyrimidines
2CreatorAuthor's name, affiliation, country G. VEERA RAGHAVA SHARMA*, A. APPALA NAIDU and B. DEVI
GITAM Institute of Technology, GITAM University, Rushikonda, Visakhapatnam-530045, AP, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Thiazolopyrimidines, Multicomponent reaction, Solvent-free method, Tetracyclic system, Eco-friendly reactions
4DescriptionAbstract A novel, solvent-free, simple, eco-friendly and one-pot multicomponent synthesis of various thiazolopyrimidines is studied. Conventional heating the mixture of amine, aldehyde and β-ketoester or 1,3-diketone under solvent free conditions afforded the thiazolopyrimidines compound in good to excellent yields. Further, a boron trifluoride mediated intermolecular cyclization to provide a novel tetra cyclic system is also reported. 1H NMR, 13C NMR, IR and Mass spectroscopy and single crystal analysis were used for identification of these compounds.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2018.1474
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  7 , Number  (2), (2018)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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