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Electrochemical Behaviour and Differential Pulse Cathodic Adsorptive Stripping Voltammetric Determination of Carmustine

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1TitleTitle of DocumentElectrochemical Behaviour and Differential Pulse Cathodic Adsorptive Stripping Voltammetric Determination of Carmustine
2CreatorAuthor's name, affiliation, country SACHIN DOI, PRIYANKA SINHA and D. K. SHARMA*
Electrochemical Sensor Research Laboratory, Department of Chemistry, University of Rajasthan, Jaipur (Rajasthan)-302004, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Carmustine, Cyclic voltammetry, Differential pulse cathodic adsorptive stripping voltammetry, Diffusion-controlled, LOD and LOQ
4DescriptionAbstract Electrochemical reduction properties of carmustine, an anticancer medication, were studied at glassy carbon electrode using cyclic voltammetry. A well defined irreversible reduction peak was obtained at -1.001V potential vs. Ag/AgCl reference electrode in BR buffer of pH 6.3. Mass transport in the reduction process was found to be diffusion controlled and a reduction mechanism was proposed on the basis of kinetic parameters which were calculated using experimental data. Furthermore, determination of carmustine in bulk form and human urine as a biological sample was carried out by differential pulse cathodic adsorptive stripping voltammetry using optimised parameters. Peak current was linear in the concentration range of 6.5x10-6-1.065x10-3M. LOD and LOQ were observed to be 4.16x10-7M and 1.39x10-6M respectively
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  7 , Number  (3), (2018)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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