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Synthesis, Characterization, In Vitro Anti-diabetic, Antibacterial and Anticorrosive Activity of Some Cr(III) Complexes of Schiff Bases Derived from Isoniazid

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1TitleTitle of DocumentSynthesis, Characterization, In Vitro Anti-diabetic, Antibacterial and Anticorrosive Activity of Some Cr(III) Complexes of Schiff Bases Derived from Isoniazid
2CreatorAuthor's name, affiliation, country SATYENDRA N. SHUKLA1*, PRATIKSHA GAUR1, SANGEETA JHARIYA1, BHASKAR CHAURASIA1, PREETI VAIDYA1, DIMPLE DEHARIYA1 and M. AZAM2/sup>
1Coordination Chemistry Research Lab, Department of Chemistry, Govt. Science College, Jabalpur (M.P.), India
2King Saud University, Riyadh, Saudi Arabia
3SubjectDicipline(s) Chemical Science
3SubjectKeywords α-Amylase, Schiff bases, isoniazid, Type II diabetes, Chromium(III) complex
4DescriptionAbstract Four complexes of Cr(III) were synthesized with Schiff bases ligands derived from isonicotinyl hydrazide with benzaldehyde/ p-chlorobenzaldehyde. The ligands and complexes were characterized by elemental analysis, molar conductance, magnetic moment, FT-IR, 1H NMR, 13C{1H} NMR and electronic spectroscopy. The molecular structure and different quantum chemical parameters such as dipole moment and polarizability, were calculated using the B3LYP basis set density functional theory (DFT) with the standard 6-311+G(d, 2p) level. The calculated HOMO and LUMO energies show that charge transfer occurs within the molecules. Ligands and complexes were screened for in vitro anti-diabetic and antibacterial activity. Anticorrosion activity of complexes was also studied by weight loss method.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier DOI:10.7598/cst2018.1509
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  7 , Number  (3), (2018)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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