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Electrochemical Determination of Anesthetic Drug Ropivacaine in Pharmaceutical Formulations by Differential Pulse Cathodic Adsorptive Stripping Voltammetry

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1TitleTitle of DocumentElectrochemical Determination of Anesthetic Drug Ropivacaine in Pharmaceutical Formulations by Differential Pulse Cathodic Adsorptive Stripping Voltammetry
2CreatorAuthor's name, affiliation, country MAHADEVA SINGH JAT, VARSHA JAKHAR, K. K. JHANKAL and D. K. SHARMA*
Electrochemical Sensor Research Laboratory, Department of Chemistry, University of Rajasthan, Jaipur (Rajasthan)-302004, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Ropivacaine, Anaesthetic drug, Cathodic adsorptive stripping voltammetry, Glassy carbon electrode.
4DescriptionAbstract Electrochemical behaviour of ropivacaine at glassy carbon electrode was studied by cyclic and differential pulse cathodic adsorptive stripping voltammetry (DPCAdSV) under different experimental conditions. The voltammetric peak current and potential for the reduction of ropivacaine were analyzed at different pH, scan rate and concentration. The voltammograms exhibited irreversible reduction of ropivacaine in B.R. buffer of pH 9. The proposed method was successfully applied for the determination of the drug which is commercial liquid. The proposed differential pulse cathodic adsorptive stripping voltammetric method shows limit of detection (LOD) and limit of quantification (LOQ) are 7.79?10−7 g/mL and 4.26?10−7 g/mL respectively.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  8 , Number  (1), (2019)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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