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Synthesis and Characterization of 3-[4-(1-Acetyl-5-(substitutedphenyl)-4,5-dihydro-pyrazol-3-yl)phenyl]-6,8-dibromo-2-phenylquinazolin-4-one Derivatives and Study of their Antimicrobial Activities |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Synthesis and Characterization of 3-[4-(1-Acetyl-5-(substitutedphenyl)-4,5-dihydro-pyrazol-3-yl)phenyl]-6,8-dibromo-2-phenylquinazolin-4-one Derivatives and Study of their Antimicrobial Activities |
| 2 | Creator | Author's name, affiliation, country | KOMAL SAVALIYA1* and PANKAJ S. PATEL2
1Department of Chemistry, Sheth L.H. Science College, Mansa-382845, India
(Research Scholars of Gujarat University, Ahmedabad)
2Department of Chemistry, Sheth L.H. Science College, Mansa.-382845, India
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| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Acetyl pyrazolines, Hydrazine hydrate, Agar Cup method, Chalcone, Antimicrobial activity |
| 4 | Description | Abstract | Synthesis of new series of 3-[4-(1-acetyl-5-(substitutedphenyl)-4,5-dihydro-pyrazol-3-yl)phenyl]-6,8-dibromo-2-phenylquinazolin-4-one have been ynthesized by acylation of 6,8-dibromo-3-{4-[5-(substitutedphenyl)-4,5-dihydro-pyrazol-3-yl]phenyl}-2-phenylquinazolin-4-one using glycial acetic acid for three hours. The intermediate have been synthesized by refluxation of 6,8-dibromo-3-{4-[3-(substitutedphenyl)prop-2-enoyl]phenyl}-2-phenylquinazolin-4-one (0.01 M) and 99% hydrazine hydrate (0.015 M) by using ethanol (50 mL) as a solvent with various aldehydes. The chemical structures of the newly synthesized acetyl compounds have been confirmed on the basis of elemental analysis and spectral data. Some of the synthesized compounds exhibit significant antibacterial activity and antifungal activity. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 9 , Number (1), (2020) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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