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Antimicrobial and Anticancer Activity of Gold Nanoparticles Synthesized from Grapes Fruit Extract

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1TitleTitle of DocumentAntimicrobial and Anticancer Activity of Gold Nanoparticles Synthesized from Grapes Fruit Extract
2CreatorAuthor's name, affiliation, country S. LOKINA and V. NARAYANAN
Rajalakshmi Engineering College, Thandalam, Chennai, Tamilnadu, India
Department of Inorganic Chemistry, University of Madras, Chennai, Tamilnadu, India
3SubjectDicipline(s) Chemical Science
3SubjectKeywords Gold nanoparticles, Grapes, Polyphenols, Antimicrobial activity, Cytotoxicity
4DescriptionAbstract Bio-inspired gold nanoparticles are rapidly synthesized at room temperature using grapes fruit extract. A green and low cost synthesis is effective in the formation of stable crystalline gold nanoparticles in the solution. Polyphenols which is present in the grapes fruit extract function as reducing as well as stabilizing agent to produce shape controlled gold nanoparticles. Surface plasmon resonance confirmed the formation of gold nanoparticles in UV-Visible spectra at 500 nm. The Fourier transform infrared spectroscopy (FTIR) analysis was carried out to identify and study the functional groups responsible for the bio-reduction of gold ion. High resolution transmission electron microscopy (HRTEM) images showed the spherical crystalline gold nanoparticles. Thermogravimetric analysis (TGA) measures the weight loss of gold nanoparticles as a function of temperature under a controlled atmosphere. The synthesized gold nanoparticles showed excellent antimicrobial activity towards most of the tested fungal and bacterial culture. It showed good anticancer activity against HeLa cell lines.
5PublishersOrganizing agency, location WWW Publications, India
6Contributor Sponsor(s) -
7DateDate (YYYY-MM-DD) -
8TypeStatus & genre Peer-reviewed Article
8TypeType
9FormateFile Formate PDF
10IdentifierUniform Resource Identifier Click Here
10IdentifierDigital Object Identifier
11SourceJournal/conference title; vol., no. (Year)Chemical Science Transactions, Volume  2 , Number  (S1), (2013)
12LanuguageEnglish=en en
13RelationSupp.files
14Coverage -
15CopyrightCopyright and permissions
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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